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== What Does It Mean? ==

* Immune dysfunction refers to an imbalance in immune system function, which can manifest as increased susceptibility to infections, chronic inflammation, or autoimmune-like symptoms.
* This dysfunction may result from chronic stress, poor nutrition, gut dysbiosis, environmental toxins, or metabolic imbalances.
* Functional medicine focuses on identifying and addressing the root causes, such as nutrient deficiencies, immune dysregulation, and inflammatory triggers.

== How Did We Get Here? ==

=== Root Causes & Contributing Factors: ===

* Chronic Stress: Prolonged stress leads to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, impacting immune function.
* Nutritional Deficiencies: Inadequate levels of vitamin D, zinc, and essential fatty acids can weaken immune responses.
* Gut Dysbiosis: Imbalances in the gut microbiome contribute to systemic inflammation and immune dysfunction.
* Toxic Load: Exposure to environmental toxins, heavy metals, and mold can impair immune function.
* Metabolic Dysfunction: Insulin resistance and chronic inflammation negatively impact immune system regulation.

=== Signs & Symptoms: ===

* Frequent infections, slow wound healing, and increased susceptibility to colds and flu.
* Chronic inflammation leading to joint pain, fatigue, and brain fog.
* Allergic reactions, food sensitivities, and autoimmune-like symptoms.
* Gastrointestinal issues such as bloating, diarrhea, or leaky gut syndrome.

=== Lab Test Findings ===
The following lab tests help evaluate immune dysfunction and its underlying causes:
{| class="wikitable"
|'''Lab Test Name'''
|'''Expected Changes'''
|'''Optimal Range'''
|-
|Alkaline Phosphatase
|Altered
|45.00-100.00 U/L
|-
|Antinuclear Antibody (ANA) Screen
|Negative
|Negative
|-
|Antistreptolysin O (ASO) Antibody
|Altered
|0.00-200.00 IU/mL
|-
|AST (SGOT)
|Altered
|10.00-26.00 U/L
|-
|Basophil %
|Altered
|0.00-1.00%
|-
|C-Reactive Protein (hs-CRP)
|Increased
|0.00-0.55 mg/L
|-
|Eosinophil %
|Altered
|0.00-3.00%
|-
|Erythrocyte Sedimentation Rate (ESR)
|Increased
|0-1.00 mm/hr
|-
|Globulin
|Altered
|2.40-2.80 g/dL
|-
|Lymphocyte %
|Altered
|30.00-40.00%
|-
|Monocyte %
|Altered
|4.00-7.00%
|-
|Neutrophil %
|Altered
|48.00-60.00%
|-
|Total Iron Binding Capacity
|Altered
|250.00-350.00 µg/dL
|-
|UIBC
|Altered
|130.00-300.00 µg/dL
|-
|WBC
|Altered
|5.5-7.510^9/L
|}

== How Do We Treat It? ==
Treatment focuses on restoring immune balance, reducing inflammation, and optimizing immune resilience.

=== Supplement Protocol ===
{| class="wikitable"
|'''Supplement'''
|'''Function'''
|'''Dosage & Frequency'''
|-
|Advanced Vita-Biotic R
|Supports immune modulation and gut health
|1 capsule with food, daily
|-
|Endura
|Aids in electrolyte balance and hydration
|1 packet with or without food, three times daily 
|-
|D-Mannose Powder
|Supports urinary tract and immune function
|1 tsp of powder with food, twice daily
|-
|CoQ-10 300 mg
|Provides antioxidant support for cellular health
|2 capsules with food, daily
|-
|N-Acetyl Cysteine
|Supports detoxification and antioxidant activity
|1 capsule without food, daily
|-
|Vita DIM
|Supports estrogen metabolism and immune balance
|2 capsules with or without food, daily
|-
|Zinc
|Essential for immune cell function
|1 capsule with food, daily
|-
|Vita-Digestyzyme
|Enhances digestion and nutrient absorption
|2 capsule 20-30 minutes prior to food, twice daily
|-
|Vita-Glutathione
|Antioxidant that supports detoxification and immunity
|1 capsule with or without food, daily
|-
|Vita-Candid
|Helps regulate gut microbiome balance
|2 capsules 20-30 minutes prior to food, twice daily
|-
|Vita B Methyl
|Supports energy production and immune function
|1 capsule without food, daily
|-
|V-Pax
|Aids in inflammation reduction and immune balance
|2  capsules with or without food, twice daily
|-
|V-Inflamma
|Reduces chronic inflammation
|1 capsule without food, daily
|-
|Vita Defense
|Immune system support
|1 capsule without food, daily
|-
|Magnesium
|Supports immune and nervous system function
|2 capsules with or without food, daily
|-
|V-Collagen
|Promotes tissue repair and immune integrity
|1 scoop of powder without food, daily
|-
|SBI Powder
|Enhances gut barrier integrity and immune modulation
|1 scoop of powder in cold liquids without food, daily
|-
|Gluta Protect
|Supports liver detoxification and immune function
|1 scoop of powder without food, daily
|-
|Vita Microbe
|Probiotic blend for gut and immune health
|3  capsules with or without food, daily
|-
|Vita Buffered C Powder
|Provides immune-boosting vitamin C
|¼  scoop of powder with food, twice daily
|-
|Vita-Biotic
|Comprehensive immune support formula
|4 capsule without food, daily
|-
|Vita-Flux
|Supports nitric oxide production and vascular health
|2 capsules 20-30 minutes  prior to food, twice daily
|}

=== Additional Lifestyle Interventions: ===

* Optimize Nutrition: Include immune-supportive foods such as leafy greens, berries, and lean proteins.
* Gut Health Support: Incorporate probiotics and prebiotics to promote a balanced microbiome.
* Stress Reduction: Engage in meditation, breathwork, and mindfulness practices to regulate stress responses.
* Reduce Toxic Exposure: Minimize exposure to heavy metals, mold, and environmental toxins.