View source for Tissue Inflammation & Destruction

== What Does It Mean? ==
Tissue Inflammation & Destruction refers to chronic or acute inflammatory responses that lead to structural damage and dysfunction in tissues. Persistent inflammation can result in oxidative stress, impaired healing, and increased risk for degenerative diseases.

== How Did We Get There? ==

=== Root Causes: ===

* Chronic Inflammatory Stimuli – Persistent infections, autoimmune conditions, or toxic exposure.
* Oxidative Stress & Free Radicals – Excess oxidative damage accelerates tissue breakdown.
* Poor Nutrient Status – Deficiencies in key anti-inflammatory nutrients impair tissue repair.
* Metabolic Dysfunction – Insulin resistance and lipid imbalances promote systemic inflammation.
* Mitochondrial Dysfunction – Reduced cellular energy output hinders healing and immune function.

=== Signs & Symptoms: ===

* Chronic pain and stiffness
* Joint swelling or limited mobility
* Fatigue and brain fog
* Delayed wound healing
* Digestive disturbances (if gut inflammation is present)
* Increased risk of degenerative conditions

== Lab Test Findings ==
{| class="wikitable"
|'''Lab Test Name'''
|'''Expected Change'''
|'''Optimal Range'''
|-
|Alkaline Phosphatase
|Increased
|45.00-100.00 IU/L
|-
|Apolipoprotein A-1
|Decreased
|150.00-210.00 mg/dL
|-
|Arachidonic Acid (AA)
|Elevated
|8.6-15.6 % by weight
|-
|Atherogenic Index of Plasma (AIP)
|Elevated
|<nowiki>-0.61 Index</nowiki>
|-
|Basophil %
|Increased
|0.00-1.00 %
|-
|Basophil Abs
|Increased
|0.00-0.07 cells/µL
|-
|Calcium: Phosphorus Ratio
|Increased or Decreased
|2.30-3.20 µg/mL
|-
|Docosahexaenoic acid (DHA)
|Increased or Decreased
|1.2-3.9 µg/mL
|-
|Docosapentaenoic acid (DPA)
|Increased or Decreased
|0.8-1.8 µg/mL
|-
|Eicosapentaenoic Acid (EPA)
|Increased or Decreased
|0.2-2.3 µg/mL
|-
|Erythrocyte Sedimentation Rate (ESR) 
|Increased
|0.00-1.00 mm/hr
|-
|Immature Granulocyte %
|Increased
|0.00-0.50 cells/µL
|-
|Immature Granulocyte Abs
|Increased
|0.00-0.03 cells/µL
|-
|Linoleic Acid
|Increased or Decreased
|18.6-29.5 µg/mL
|-
|Neutrophil: Lymphocyte Ratio
|Increased
|1.00-1.70
|-
|Omega-6: Omega-3 Ratio
|Increased
|3.7-14.4
|-
|Phosphatidylcholine IgA Ab
|Present
|0-12.0 mg/dL
|-
|Phosphatidylcholine IgG Ab
|Present
|0-12.0 mg/dL
|-
|Phosphatidylcholine IgM Ab
|Present
|0-12.0 mg/dL
|-
|Platelet: Lymphocyte (PLR) Ratio
|Increased or Decreased
|0.00-128.00
|-
|Potassium
|Increased or Decreased
|4.00-4.50 mEq/L
|-
|Sodium: Potassium Ratio
|Increased or Decreased
|30.00-35.00
|}

== How Do We Treat It? ==

=== Functional Medicine Approach: ===
Reducing inflammation and supporting tissue repair through targeted nutrients and lifestyle modifications.

=== Supplement Protocol ===
{| class="wikitable"
|'''Supplement'''
|'''Function''' 
|'''Dosage & Frequency'''
|-
|Vita Buffered C Powder
|Provides potent antioxidant protection to combat oxidative stress
|1 scoop of powder without food, daily
|-
|Glucosamine Sulfate
|Supports joint and connective tissue health
|1 capsule without food, twice daily
|-
|V-Inflamma
|Reduces systemic inflammation and supports immune modulation
|2 capsules without food, daily
|-
|Vascuzyme
|Supports vascular and inflammatory balance
|2 capsules without food, daily
|-
|V-Pax
|Enhances mitochondrial function and cellular recovery
|2 capsules without food, daily
|-
|N-Acteyl Cysteine             
|Supports detoxification, and acts as an antioxidant to protect cells from oxidative damage
|1 capsule without food, daily 
|-
|V-Collagen 
|Supports gut lining & joint health 
|1 scoop of powder without food, daily 
|-
|Vita Glutathione
|Antioxidant & cellular detoxification
|2 capsules with or without food, daily 
|}

=== Additional Lifestyle Interventions: ===

* Anti-Inflammatory Diet: Focus on whole foods, healthy fats, and antioxidant-rich vegetables.
* Exercise & Movement: Moderate movement to enhance circulation and reduce stiffness.
* Stress Reduction: Mindfulness, meditation, and breathing exercises to lower cortisol levels.
* Reduce Toxin Load: Minimize exposure to environmental toxins, heavy metals, and processed foods.
* Monitor Inflammatory Markers: Regular lab assessments to track progress and adjust interventions.