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	<id>https://wiki.bioinsights.com/w/index.php?action=history&amp;feed=atom&amp;title=Hyperuricemia</id>
	<title>Hyperuricemia - Revision history</title>
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	<updated>2026-05-06T07:28:38Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<id>https://wiki.bioinsights.com/w/index.php?title=Hyperuricemia&amp;diff=194&amp;oldid=prev</id>
		<title>Kelly.oconnor: Created</title>
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		<updated>2025-05-08T02:45:02Z</updated>

		<summary type="html">&lt;p&gt;Created&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== What Does It Mean? ==&lt;br /&gt;
&lt;br /&gt;
* Hyperuricemia is a condition characterized by elevated uric acid levels in the blood, which may lead to gout, kidney stones, and cardiovascular complications.&lt;br /&gt;
* It results from an imbalance between uric acid production and excretion, often influenced by diet, metabolic dysfunction, and renal clearance capacity.&lt;br /&gt;
* Functional medicine focuses on identifying root causes such as metabolic dysfunction, oxidative stress, inflammation, and impaired detoxification pathways.&lt;br /&gt;
&lt;br /&gt;
== How Did We Get Here? ==&lt;br /&gt;
&lt;br /&gt;
=== Root Causes &amp;amp; Contributing Factors: ===&lt;br /&gt;
&lt;br /&gt;
* Dietary Factors: High intake of purine-rich foods (red meat, shellfish), excessive fructose, and alcohol consumption.&lt;br /&gt;
* Renal Dysfunction: Impaired kidney function leads to reduced uric acid excretion.&lt;br /&gt;
* Metabolic Dysfunction: Insulin resistance and obesity increase uric acid production and retention.&lt;br /&gt;
* Inflammation &amp;amp; Oxidative Stress: Chronic inflammation can exacerbate hyperuricemia by impairing normal metabolic processes.&lt;br /&gt;
* Genetics &amp;amp; Epigenetics: Some individuals have genetic predispositions to inefficient uric acid metabolism.&lt;br /&gt;
&lt;br /&gt;
=== Signs &amp;amp; Symptoms: ===&lt;br /&gt;
&lt;br /&gt;
* Joint pain, swelling, and tenderness, commonly in the big toe (indicative of gout).&lt;br /&gt;
* Kidney stones or symptoms of renal impairment (flank pain, urinary issues).&lt;br /&gt;
* Fatigue and systemic inflammation-related symptoms.&lt;br /&gt;
* Elevated blood pressure or cardiovascular concerns related to high uric acid levels.&lt;br /&gt;
&lt;br /&gt;
=== Lab Test Findings ===&lt;br /&gt;
The following lab tests help evaluate hyperuricemia and its underlying causes:&lt;br /&gt;
{| class=&amp;quot;wikitable&amp;quot;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Lab Test Name&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Expected Changes&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Optimal Ranges&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|-&lt;br /&gt;
|Blood Urea Nitrogen (BUN)&lt;br /&gt;
|Increased&lt;br /&gt;
|10.00-16.00 mg/dL&lt;br /&gt;
|-&lt;br /&gt;
|Cholesterol, Serum&lt;br /&gt;
|Increased&lt;br /&gt;
|180.00-220.00 mg/dL&lt;br /&gt;
|-&lt;br /&gt;
|Phosphorus (Phosphate)&lt;br /&gt;
|Altered&lt;br /&gt;
|3.00-4.00 mg/dL&lt;br /&gt;
|-&lt;br /&gt;
|Uric Acid (Male)&lt;br /&gt;
|Increased&lt;br /&gt;
|3.50-5.40 mg/dL&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== How Do We Treat It? ==&lt;br /&gt;
Treatment aims to address root causes, improve uric acid metabolism, and support detoxification pathways.&lt;br /&gt;
&lt;br /&gt;
=== Supplement Protocol ===&lt;br /&gt;
{| class=&amp;quot;wikitable&amp;quot;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Supplement&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Function&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|&amp;#039;&amp;#039;&amp;#039;Dosage &amp;amp; Frequency&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
|-&lt;br /&gt;
|Vita-Flux&lt;br /&gt;
|Supports nitric oxide production and vascular health&lt;br /&gt;
|2 capsules 20-30 minutes  prior to food, daily&lt;br /&gt;
|-&lt;br /&gt;
|Vita-Uric Pro&lt;br /&gt;
|Helps reduce uric acid levels and supports kidney function&lt;br /&gt;
|3 capsules without food, daily&lt;br /&gt;
|-&lt;br /&gt;
|V-Pax&lt;br /&gt;
|Enhances mitochondrial function and metabolic balance&lt;br /&gt;
|2  capsules without food, daily&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
=== Additional Lifestyle Interventions: ===&lt;br /&gt;
&lt;br /&gt;
* Dietary Adjustments: Reduce purine-rich foods, limit fructose intake, increase hydration.&lt;br /&gt;
* Kidney Support: Optimize renal function with adequate water intake and kidney-supportive nutrients.&lt;br /&gt;
* Metabolic Balance: Maintain healthy blood sugar levels to reduce uric acid retention.&lt;br /&gt;
* Inflammation Reduction: Incorporate anti-inflammatory foods and nutrients such as turmeric and omega-3 fatty acids.&lt;/div&gt;</summary>
		<author><name>Kelly.oconnor</name></author>
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