Kelly.oconnor: Created

2025-05-07T23:08:40Z

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== What Does It Mean? ==

* Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body, leading to cellular damage.
* Functional medicine addresses oxidative stress by identifying root causes such as inflammation, toxin exposure, and nutritional deficiencies.

== How Did We Get Here? ==

=== Root Causes & Contributing Factors: ===

* Chronic Inflammation: Persistent inflammation increases oxidative stress.
* Nutrient Deficiencies: Low levels of antioxidants reduce the body's ability to neutralize free radicals.
* Environmental Toxins: Exposure to pollutants, heavy metals, and chemicals contributes to oxidative damage.
* Poor Diet: High intake of processed foods and refined sugars can increase free radical production.
* Mitochondrial Dysfunction: Impaired cellular energy production leads to increased oxidative stress.

=== Signs & Symptoms: ===

* Fatigue and brain fog
* Premature aging and skin issues
* Increased susceptibility to infections
* Chronic pain and joint discomfort
* Neurological symptoms such as headaches or cognitive decline

=== Diagnostic Lab Findings ===
The following lab tests assess oxidative stress and free radical activity:
{| class="wikitable"
|'''Lab Test Name'''
|'''Expected Changes'''
|'''Optimal Range'''
|-
|Albumin
|Decreased
|4.50-5.00 g/dL
|-
|Bilirubin, Total
|Normal/Decreased
|0.50-0.90 mg/dL
|-
|Cholesterol, Serum
|Increased
|180.00-220.00 mg/dL
|-
|Copper : Zinc Ratio
|Imbalanced
|0.70-1.50
|-
|Ferritin
|Increased
|45.00-79.00 ng/mL
|-
|Free T3 : Reverse T3 Ratio
|Decreased
|10.00-28.00
|-
|Globulin
|Normal
|2.40-2.80 g/dL
|-
|Glutathione
|Decreased
|373.00-838.00 µM
|-
|LDL Cholesterol Direct
|Increased
|80.00-99.99 mg/dL
|-
|Lymphocyte %
|Normal
|30.00-40.00 %
|-
|MPV
|Increased
|7.50-8.20 fL
|-
|Platelet Count
|Normal
|190.00-300.00 cells/µL
|-
|Uric Acid
|Increased
|3.50-5.40 mg/dL
|}

== How Do We Treat It? ==
Treatment focuses on reducing oxidative stress, enhancing antioxidant levels, and improving detoxification pathways.

=== Supplement Protocol ===
{| class="wikitable"
|'''Supplement'''
|'''Function'''
|'''Dosage & Frequency'''
|-
|V-Pax
|Provides comprehensive micronutrient support
|2 capsules with food, twice daily
|-
|CoQ-10 300 mg
|Supports mitochondrial function and cellular energy
|2 capsules with food, daily
|-
|V-Inflamma
|Reduces systemic inflammation and neutralizes free radicals
|1 capsule without food, daily
|-
|Vita-Glutathione
|Enhances detoxification and antioxidant protection
|1 capsule with or without food, daily
|}

=== Additional Lifestyle Interventions: ===

* Antioxidant-Rich Diet: Increase intake of berries, leafy greens, and healthy fats.
* Reduce Toxin Exposure: Avoid processed foods, limit alcohol, and reduce exposure to environmental pollutants.
* Hydration & Detoxification: Support liver function with adequate hydration and detox-supporting foods.
* Regular Physical Activity: Engage in moderate exercise to enhance circulation and reduce oxidative stress.
* Stress Management: Reduce cortisol-induced oxidative stress through mindfulness, deep breathing, and relaxation techniques.

Oxidative Stress / Free Radical Activity - Revision history

Kelly.oconnor: Created