Depression - Male
What Does It Mean?
Depression is a chronic mental health disorder that affects mood, cognition, and overall well-being. In men, depression often manifests differently than in women, with increased irritability, aggression, substance use, and social withdrawal. Functional Medicine considers depression a symptom of deeper physiological imbalances rather than a standalone condition.
How Did We Get There?
Root Causes:
- Neurotransmitter Dysregulation – Deficiencies in serotonin, dopamine, and norepinephrine contribute to mood instability.
- Chronic Inflammation – Elevated inflammatory markers such as C-reactive protein (CRP) can impair brain function.
- HPA Axis Dysfunction – Cortisol imbalances contribute to adrenal fatigue and mood disturbances.
- Gut Dysbiosis – The gut-brain axis influences mental health, and an imbalanced microbiome can lead to depressive symptoms.
- Nutrient Deficiencies – Low levels of B vitamins, magnesium, and omega-3 fatty acids are linked to depressive symptoms.
- Heavy Metal & Toxin Accumulation – Elevated levels of metals such as aluminum and lead may contribute to neurological dysfunction.
Signs & Symptoms:
- Persistent low mood or irritability
- Fatigue and decreased motivation
- Cognitive fog and difficulty concentrating
- Sleep disturbances (insomnia or excessive sleep)
- Appetite changes (increase or decrease)
- Increased aggression or risk-taking behavior
- Social withdrawal or isolation
How Do We Treat It?
A Functional Medicine approach focuses on reducing inflammation, restoring neurotransmitter balance, and optimizing nutrient status.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Advanced Vita-Biotic R | Supports gut health, reduces inflammation, promotes neurotransmitter production | 1 capsule with food, daily |
| Endura | Enhances hydration and supports adrenal function | 1 packet with or without food, three times daily |
| D-Mannose Powder | Supports gut microbiota balance | 1 tsp of powder with food, twice daily |
| Vita-Candid | Helps regulate gut microbiota | 2 capsules 20-30 minutes prior to food, daily |
| 5-HTP | Precursor to serotonin, supports mood regulation | 4 capsules with or without food, daily |
| Vita-Digestyzyme | Supports digestion and nutrient absorption | 2 capsule 20-30 minutes prior to food, twice daily |
| V-Inflamma | Reduces systemic inflammation | 1 capsule without food, daily |
| V-Pax | Supports neurological function and mood stabilization | 2 capsules with food, twice daily |
| Vita Defense | Boosts immune function and protects against oxidative stress | 1 capsule without food,daily |
| CoQ-10 300 mg | Supports mitochondrial function and energy production | 2 capsules with food, daily |
| Vita DIM | Supports hormonal balance and estrogen metabolism | 2 capsules with or without food, daily |
| Vita B Methyl | Supports methylation and neurotransmitter synthesis | 1 capsule without food, daily |
| Vita-Glutathione | Supports detoxification and oxidative stress reduction | 1 capsule with or without food, daily |
| Magnesium | Essential for relaxation and neurotransmitter production | 2 capsule with or without food, daily |
| Gluta Protect | Enhances glutathione levels for detoxification | 1 scoop of powder without food, daily |
| SBI Powder | Supports gut barrier function and immune modulation | 1 scoop of powder in cold liquids,daily |
| V-Collagen | Supports tissue repair and overall wellness | 1 scoop of powder without food, daily |
| Vita Microbe | Supports microbiome balance and immune function | 3 capsules with or without food, daily |
| Vita Buffered C Powder | Provides antioxidant support and enhances immune function | ¼ scoop of powder with food, twice daily |
| Vita-Biotic | Supports gut health and neurotransmitter production | 4 capsule without food, daily |
| Vita-Flux | Enhances nitric oxide production for improved circulation and brain function | 2 capsules 20-30 minutes prior to food, twice daily |
Additional Lifestyle Interventions:
- Dietary Support: Focus on an anti-inflammatory, high-nutrient diet rich in omega-3s and antioxidants.
- Gut Health Optimization: Probiotic-rich foods and targeted supplementation.
- Stress Management: Meditation, yoga, and mindfulness techniques.
- Exercise: Regular physical activity to enhance endorphin release.
- Sleep Optimization: Prioritize restorative sleep with proper sleep hygiene.