Edema / Non-Potassium Sparing
What Does It Mean?
Edema-Non Potassium Sparing refers to fluid retention that occurs due to an imbalance in electrolytes, particularly from diuretic use or conditions that cause excessive sodium retention and potassium loss. This can lead to swelling, cardiovascular strain, and poor circulation. Functional Medicine evaluates this condition by identifying root causes such as hormone imbalances, kidney dysfunction, and dietary factors that contribute to fluid imbalance.
How Did We Get There?
Root Causes:
- Diuretic Use (Non-Potassium Sparing) – Leads to potassium depletion and electrolyte imbalance.
- Sodium Retention – Excess dietary sodium causes increased water retention.
- Kidney Dysfunction – Impaired filtration can lead to loss of potassium and excess sodium retention.
- Aldosterone Imbalance – Increased aldosterone leads to sodium retention and potassium loss.
- Chronic Inflammation – Inflammatory processes contribute to poor fluid regulation.
- Hormonal Dysregulation – Estrogen and cortisol imbalances can worsen fluid retention.
Signs & Symptoms:
- Swelling in the legs, ankles, and feet
- Muscle weakness or cramps due to potassium loss
- High blood pressure
- Puffiness in the face and hands
- Fatigue and lightheadedness
- Decreased urine output despite fluid retention
Lab Test Findings
(Note: Additional lab tests may be referenced for a comprehensive evaluation.)
| Lab Test Name | Expected Changes | Optimal Range |
| Albumin, Serum | Decreased | 4.50-5.00 g/dL |
| Blood Urea Nitrogen (BUN) | Increased | 10.00-16.00 mg/dL |
| Magnesium, Serum | Decreased | 2.20-2.50 mg/dL |
| Potassium, Serum | Decreased | 4.00-4.50 mEq/L |
| Sodium, Serum | Increased | 137.00-142.00 mEq/L |
| Uric Acid | Increased | 3.50-5.40 mg/dL |
How Do We Treat It?
A Functional Medicine approach focuses on restoring electrolyte balance, reducing fluid retention, and supporting kidney and cardiovascular health.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Reacted Magnesium & Potassium | Supports electrolyte balance and hydration | 2 capsules with or without food, daily |
Additional Lifestyle Interventions:
- Increase Potassium Intake: Include potassium-rich foods such as avocados, bananas, and leafy greens.
- Reduce Sodium Intake: Minimize processed foods to prevent excessive fluid retention.
- Hydration Optimization: Encourage adequate water intake to support kidney function.
- Lymphatic Drainage Support: Incorporate dry brushing and movement to improve circulation.
- Monitor Diuretic Use: Consider alternative fluid regulation strategies if necessary.