What Does It Mean?
Prostate-specific antigen (PSA) is a protein produced by the prostate gland. Elevated PSA levels can indicate prostate inflammation, benign prostatic hyperplasia (BPH), infection, or, in some cases, prostate cancer. Functional Medicine evaluates Elevated PSA by identifying the underlying causes of inflammation and hormone imbalances while addressing prostate health through targeted interventions.
How Did We Get There?
Root Causes:
- Chronic Inflammation – Persistent inflammation in the prostate gland can contribute to elevated PSA levels.
- Hormonal Imbalances – High levels of dihydrotestosterone (DHT) and estrogen dominance can contribute to prostate enlargement and inflammation.
- Oxidative Stress & Toxin Accumulation – Environmental toxins and poor detoxification pathways may contribute to prostate dysfunction.
- Infections (Prostatitis) – Bacterial infections can cause acute or chronic prostate inflammation, leading to increased PSA levels.
- Poor Circulation & Lymphatic Drainage – Stagnation in prostate circulation may impair detoxification and healing.
- Dietary & Lifestyle Factors – High intake of processed foods, dairy, and alcohol can increase inflammation and hormonal imbalance.
Signs & Symptoms:
- Urinary urgency or frequency
- Weak or interrupted urine flow
- Pain or discomfort in the pelvic region
- Difficulty starting or stopping urination
- Erectile dysfunction
- Blood in urine or semen (in rare cases)
Lab Test Findings
(Note: Additional lab tests may be referenced for a comprehensive evaluation.)
| Lab Test Name | Expected Changes | Optimal Range |
| Bacteria | Few | None |
| Blood | Positive | negative |
| Creatinine | Increased | 0.80-1.10mg/dL |
| DHEA Sulfate | Increased or Decreased | 150.00-250.00 ug/dL |
| Dihydrotestosterone, LCMSMS | Increased | 50.00-65.00 ug/dL |
| Follicle-Stimulating Hormone (FSH) | Altered | 1.60-8.00 mlU/mL |
| Luteinizing Hormone | Altered | 1.50-6.15 mlU/mL |
| Monocyte % | Altered | 4.00-7.00 % |
| Monocyte Abs | Altered | 0.20-0.60 10(3)/uL |
| Nitrite | Altered | Negative |
| PSA, Total | Increased | 0.00-2.00 ng/mL |
| RBC’s | Altered | None |
| Spermatozoa | Altered | None |
| WBC’s | Increased | 0 |
How Do We Treat It?
A Functional Medicine approach focuses on reducing inflammation, balancing hormones, optimizing detox pathways, and improving prostate circulation to lower PSA levels naturally.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Hormone Plus | Supports hormonal balance | 2 capsule with or without food, daily |
| V-Pax | Supports neurotransmitter and prostate function | 2 capsules without food, daily |
| Vita-Thyro | Supports thyroid function and metabolism | 2 capsules with or without food, twice daily |
| Vita-Biotic | Supports gut microbiome and immune health | 2 capsules without food, daily |
Additional Lifestyle Interventions:
- Reduce Inflammatory Foods: Avoid processed foods, dairy, alcohol, and high sugar intake.
- Support Hormonal Balance: Increase cruciferous vegetables and fiber to aid estrogen metabolism.
- Optimize Detoxification: Support liver function through hydration, sauna therapy, and liver-supporting nutrients.
- Regular Physical Activity: Engage in regular exercise to improve circulation and lymphatic drainage.
- Prostate-Specific Exercises: Kegel exercises and pelvic floor therapy may improve prostate function.