What Does It Mean?
Cognitive function refers to the ability of the brain to process thoughts, retain memories, and maintain problem-solving skills. Mild cognitive impairment (MCI) is the stage between normal age-related cognitive decline and more severe neurodegenerative diseases like dementia or Alzheimer's disease. Cognitive decline can stem from various factors, including oxidative stress, neuroinflammation, mitochondrial dysfunction, and metabolic imbalances.
How Did We Get There?
Root Causes:
• Chronic Inflammation & Oxidative Stress – Increased neuroinflammation and free radical damage contribute to neuronal loss.
• Nutrient Deficiencies – Insufficient levels of B vitamins, omega-3 fatty acids, and antioxidants impair brain function.
• Mitochondrial Dysfunction – Reduced ATP production affects neuronal energy metabolism and cognitive performance.
• Glucose Dysregulation & Insulin Resistance – Poor blood sugar control leads to reduced brain fuel supply, sometimes referred to as "Type 3 Diabetes."
• Toxic Load & Heavy Metals – Exposure to environmental toxins such as mercury and aluminum may contribute to neurodegeneration.
• Chronic Stress & HPA Axis Dysregulation – Elevated cortisol levels from chronic stress can shrink the hippocampus, impairing memory and learning.
• Poor Circulation & Endothelial Dysfunction – Reduced blood flow to the brain leads to cognitive impairment.
Signs & Symptoms:
• Memory lapses and difficulty recalling information
• Struggles with problem-solving or decision-making
• Brain fog and mental fatigue
• Difficulty concentrating
• Changes in mood, including anxiety and irritability
• Reduced processing speed and slower learning ability
How Do We Treat It?
Supplement Protocol:
The protocol provided in the dataset recommends referral to a neurologist or psychiatrist for further evaluation. However, in a functional medicine approach, cognitive function can be supported through targeted supplementation, lifestyle interventions, and neuroprotective strategies.
Additional Lifestyle Interventions:
• Brain-Boosting Diet: Incorporate a Mediterranean or ketogenic diet rich in healthy fats, antioxidants, and low-glycemic carbohydrates.
• Support Mitochondrial Health: Ensure proper intake of CoQ10, B vitamins, and magnesium to enhance energy production.
• Manage Blood Sugar: Reduce processed sugars and refined carbohydrates to prevent insulin resistance and neurodegeneration.
• Reduce Inflammatory Triggers: Avoid processed foods, manage gut health, and optimize omega-3 to omega-6 ratios.
• Improve Circulation: Engage in regular cardiovascular exercise to enhance cerebral blood flow.
• Cognitive Stimulation: Encourage reading, learning new skills, and engaging in memory-boosting activities.
• Stress Management: Practice mindfulness, meditation, and adequate sleep hygiene to reduce cortisol levels and support cognitive resilience.