What Does It Mean?
Erectile Dysfunction (ED) is the inability to achieve or maintain an erection sufficient for sexual intercourse. It is often a symptom of underlying imbalances related to cardiovascular health, hormone function, inflammation, and neurological regulation. Functional Medicine approaches Erectile Dysfunction by addressing the root causes such as vascular dysfunction, oxidative stress, and hormonal imbalances.
How Did We Get There?
Root Causes:
- Endothelial Dysfunction – Poor circulation and reduced nitric oxide production impair blood flow to the penis.
- Hormonal Imbalances – Low testosterone, elevated estrogen, and cortisol dysregulation contribute to ED.
- Chronic Inflammation & Oxidative Stress – Increased free radicals damage blood vessels and reduce nitric oxide levels.
- Metabolic Dysfunction – Insulin resistance and high blood sugar impact vascular health.
- Neurological Dysfunction – Autonomic nervous system imbalances affect arousal and response.
- Psychological Factors – Stress, anxiety, and depression can inhibit sexual function.
Signs & Symptoms:
- Difficulty achieving or maintaining an erection
- Decreased libido or sexual desire
- Fatigue and low energy levels
- Poor recovery after exercise
- Mood imbalances, including anxiety or depression
- Increased abdominal fat and reduced muscle mass (indicative of low testosterone)
Lab Test Findings
(Note: Additional lab tests may be referenced for a comprehensive evaluation.)
| Lab Test Name | Expected Changes | Optimal Range |
| Albumin : Globulin Ratio | Altered | 1.00-2.50 Ratio |
| Dihydrotestosterone, LCMSMS | Increased | 12.00-65.00 ug/dL |
| Estradiol-E2 | Increased | 0.00-39.00 pg/mL |
| Estrogen | Increased | 56-213 pg/mL |
| Follicle-Stimulating Hormone (FSH) | Altered | 1.60-8.00 mlU/mL |
| Luteinizing Hormone | Altered | 1.50-9.30 mlU/mL |
| Testosterone, Total | Decreased | 250.00-1100.00 ng/dL |
How Do We Treat It?
A Functional Medicine approach focuses on improving vascular health, balancing hormones, reducing inflammation, and supporting nervous system function to optimize erectile function.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Hormone Plus | Supports hormonal balance and androgen metabolism | 2 capsules without food, daily |
| Vita DIM | Supports estrogen metabolism and hormonal regulation | 2 capsules with or without food, daily |
| CitraNOX | Enhances nitric oxide production for vascular health | 2 capsules with food, twice daily |
Additional Lifestyle Interventions:
- Increase Nitric Oxide Production: Consume nitrate-rich foods such as beets, leafy greens, and pomegranate.
- Optimize Testosterone Levels: Engage in resistance training, ensure adequate sleep, and reduce environmental xenoestrogens.
- Support Cardiovascular Health: Improve endothelial function through regular physical activity and stress management.
- Reduce Sugar & Processed Foods: Minimize insulin resistance and support metabolic balance.
- Manage Psychological Factors: Address anxiety, depression, and relationship stress through therapy or mindfulness techniques.