Molybdenum Deficiency

What Does It Mean?

Molybdenum is an essential trace mineral required for the function of several important enzymes, including those involved in detoxification and metabolism.
Deficiency can impair the body's ability to break down sulfites, purines, and certain toxins, leading to metabolic dysfunction and neurological issues.
Functional medicine focuses on restoring adequate molybdenum levels to support detoxification and enzymatic function.

Poor Dietary Intake: Deficiency may result from a diet low in molybdenum-rich foods (legumes, whole grains, nuts, leafy greens).
Gastrointestinal Malabsorption: Conditions such as Crohn’s disease, celiac disease, or chronic gut inflammation may impair molybdenum absorption.
High Sulfite Exposure: Molybdenum plays a role in sulfite metabolism; excessive exposure to sulfites (e.g., processed foods, preservatives) can deplete stores.
Genetic Factors: Certain genetic polymorphisms can impair molybdenum metabolism and enzyme function.
Heavy Metal Toxicity: Exposure to toxic metals (e.g., lead, mercury) may interfere with molybdenum-dependent enzymatic activity.

The following lab test helps assess molybdenum status:

Lab Test Name	Expected Changes	Optimal Range
Molybdenum, Blood	Decreased	0.00-2.20 µg/L

Treatment focuses on replenishing molybdenum levels, supporting detoxification, and optimizing enzymatic activity.

Supplement	Function	Dosage & Frequency
OsteoPrev	Supports mineral balance and molybdenum levels	2 capsules with food, daily

Increase Dietary Sources: Consume more legumes, nuts, seeds, whole grains, and leafy greens to boost molybdenum intake.
Reduce Sulfite Exposure: Avoid sulfite-rich processed foods, dried fruits, and preservatives.
Enhance Detoxification Pathways: Support liver detox with cruciferous vegetables, adequate hydration, and sauna therapy.
Monitor & Retest: Periodic lab testing to assess molybdenum status and enzymatic function.