What Does It Mean?
- Molybdenum is an essential trace mineral required for the function of several important enzymes, including those involved in detoxification and metabolism.
- Deficiency can impair the body's ability to break down sulfites, purines, and certain toxins, leading to metabolic dysfunction and neurological issues.
- Functional medicine focuses on restoring adequate molybdenum levels to support detoxification and enzymatic function.
How Did We Get Here?
Root Causes & Contributing Factors:
- Poor Dietary Intake: Deficiency may result from a diet low in molybdenum-rich foods (legumes, whole grains, nuts, leafy greens).
- Gastrointestinal Malabsorption: Conditions such as Crohn’s disease, celiac disease, or chronic gut inflammation may impair molybdenum absorption.
- High Sulfite Exposure: Molybdenum plays a role in sulfite metabolism; excessive exposure to sulfites (e.g., processed foods, preservatives) can deplete stores.
- Genetic Factors: Certain genetic polymorphisms can impair molybdenum metabolism and enzyme function.
- Heavy Metal Toxicity: Exposure to toxic metals (e.g., lead, mercury) may interfere with molybdenum-dependent enzymatic activity.
Signs & Symptoms:
- Neurological symptoms (brain fog, irritability, headaches)
- Sulfite sensitivity (difficulty metabolizing sulfites in food and wine)
- Fatigue and muscle weakness
- Increased susceptibility to toxic buildup
- Joint pain and inflammation
Lab Test Findings
The following lab test helps assess molybdenum status:
| Lab Test Name | Expected Changes | Optimal Range |
| Molybdenum, Blood | Decreased | 0.00-2.20 µg/L |
How Do We Treat It?
Treatment focuses on replenishing molybdenum levels, supporting detoxification, and optimizing enzymatic activity.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| OsteoPrev | Supports mineral balance and molybdenum levels | 2 capsules with food, daily |
Additional Lifestyle Interventions:
- Increase Dietary Sources: Consume more legumes, nuts, seeds, whole grains, and leafy greens to boost molybdenum intake.
- Reduce Sulfite Exposure: Avoid sulfite-rich processed foods, dried fruits, and preservatives.
- Enhance Detoxification Pathways: Support liver detox with cruciferous vegetables, adequate hydration, and sauna therapy.
- Monitor & Retest: Periodic lab testing to assess molybdenum status and enzymatic function.