What Does It Mean?
Fatty liver disease occurs when excessive fat accumulates in liver cells, leading to liver inflammation and potential damage. This condition is commonly linked to metabolic dysfunctions such as insulin resistance, obesity, and chronic inflammation.
How Did We Get There?
Root Causes:
• Insulin Resistance & Metabolic Syndrome – Excess insulin promotes fat storage in the liver
• Chronic Inflammation – Increased inflammatory cytokines contribute to liver damage
• Poor Lipid Metabolism – Impaired breakdown of fats leads to liver fat accumulation
• Toxin Overload – Exposure to environmental toxins and excessive alcohol consumption exacerbate liver stress
• Nutrient Deficiencies – Deficiencies in choline, omega-3s, and antioxidants impair liver detoxification
• Gut Dysbiosis – Imbalance in gut bacteria contributes to increased liver fat and systemic inflammation
Signs & Symptoms:
• Mild to moderate fatigue
• Unexplained weight gain or difficulty losing weight
• Right upper quadrant discomfort
• Brain fog and difficulty concentrating
• Elevated cholesterol and triglycerides
• Increased liver enzyme levels in blood tests
• Possible insulin resistance or prediabetes
• Jaundice in severe cases
Lab Test Findings
| Lab Test Name | Expected Changes | Optimal Range |
| Albumin | Decreased | 4.50-5.00 g/dL |
| ALT (SGPT) | Increased | 10.00-26.00 IU/L |
| AST (SGOT) | Increased | 10.00-26.00 IU/L |
| Cholesterol, Serum | Increased | 180.00-220.00 mg/dL |
| Cholinesterase, Serum | Altered | 1355-3299 IU/L |
| Ferritin | Altered | 45.00-79.00 ng/mL |
| Gamma Glutamyl Transferase (GGT) | Increased | 10.00-30.00 IU/L |
| HDL Cholesterol | Decreased | 55.00-93.00 mg/dL |
| LDL Cholesterol Direct | Increased | 80.00-99.99 mg/dL |
| LP-IR Score (NMR) | Altered | 0.00-27.00 % |
| Monocyte % | Altered | 4.00-7.00 % |
| Triglyceride-Glucose Index (TyG) | Increased | 0.00-4.40 Index |
| Triglycerides, Serum | Increased | 70.00-80.00 mg/dL |
| Uric Acid | Increased | 3.50-5.40 mg/dL |
| Antinuclear Antibody (ANA) Screen | May be Positive | Negative |
How Do We Treat It?
A functional medicine approach targets root causes through dietary modifications, lifestyle changes, and targeted supplementation.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Vita-Omega | Provides anti-inflammatory omega-3s to improve lipid balance | 2 capsules with food, daily |
| Vita DIM | Supports hormone metabolism and liver detoxification | 2 capsules with or without food, daily |
| V-Inflamma | Reduces systemic inflammation with turmeric and antioxidants | 4 capsules without food, daily |
| CoQ-10 300 mg | Enhances mitochondrial function and cellular energy | 1 capsule with food, daily |
| Novo Hepatic | Supports liver detoxification and reduces hepatic fat load | 1 capsule without food, twice daily |
| Levo Plasmin | Aids in circulatory health and fibrinolytic activity | 1 capsule without food, twice daily |
| Vita-Glutathione | Powerful antioxidant that supports liver detoxification | 3 capsules with or without food, daily |
| Vita-Biotic | Supports immune function and reduces systemic inflammation | 1 capsule with or without food, daily |
Additional Lifestyle Interventions:
- Anti-inflammatory Diet – Reduce processed foods, increase whole foods, and support liver function with cruciferous vegetables
- Optimize Metabolic Health – Reduce refined carbs and sugars to improve insulin sensitivity
- Regular Physical Activity – Engage in resistance training and aerobic exercise to enhance fat metabolism
- Liver Detoxification Support – Increase hydration, use herbal liver-supportive teas, and avoid alcohol and processed fats