What Does It Mean?
- Muscle atrophy is the progressive loss of muscle mass and strength, often due to aging, hormonal imbalances, or inadequate protein intake.
- Functional medicine addresses muscle atrophy by focusing on nutrition, hormonal optimization, mitochondrial function, and targeted supplementation to support muscle regeneration.
How Did We Get Here?
Root Causes & Contributing Factors:
- Hormonal Imbalances: Low testosterone, high cortisol, or inadequate DHEA levels can contribute to muscle wasting.
- Protein Deficiency: Insufficient protein intake impairs muscle repair and growth.
- Chronic Inflammation: Systemic inflammation accelerates muscle breakdown.
- Nutrient Deficiencies: Low levels of amino acids, vitamins, and minerals hinder muscle maintenance.
- Sedentary Lifestyle: Lack of resistance training and activity leads to accelerated muscle loss.
Signs & Symptoms:
- Decreased muscle mass and strength
- Fatigue and physical weakness
- Reduced exercise endurance and recovery
- Increased risk of falls and injuries
- Difficulty performing daily physical tasks
Lab Test Findings
The following lab tests assess factors contributing to muscle atrophy:
| Lab Test Name | Expected Changes | Optimal Range |
| ALT (SGPT) | Normal or Increased | 10.00-26.00 U/L |
| AST (SGOT) | Normal or Increased | 10.00-26.00 U/L |
| AST (SGOT) : ALT (SGPT) Ratio | Altered | 0.00-1.00 |
| Color | Dark/Tea-colored | Yellow |
| Cortisol : DHEA-S Ratio | Altered | 0.00-0.09 |
| Creatinine | Decreased | 0.80-1.10 mg/dL |
| Testosterone, Total (Male) | Decreased | 700.00-1100.00 ng/dL |
How Do We Treat It?
Treatment focuses on supporting muscle regeneration, hormonal balance, and optimal nutrient intake.
Supplement Protocol
| Supplement | Function | Dosage & Frequency |
| Vascuzyme | Supports circulation and reduces inflammation | 2 capsules without food, daily |
| V-Pax | Provides essential nutrients for muscle repair and hormonal balance | 2 capsules without food, daily |
| Perfect Protein | Supplies high-quality protein to support muscle regeneration | 1 scoop of powder with or without food, daily |
Additional Lifestyle Interventions:
- Increase Protein Intake: Ensure sufficient high-quality protein sources to support muscle synthesis.
- Strength Training: Implement resistance exercises to maintain and rebuild muscle mass.
- Hormonal Support: Address underlying hormonal imbalances contributing to muscle atrophy.
- Optimize Nutrient Intake: Include essential amino acids, magnesium, and antioxidants.
- Manage Inflammation: Reduce processed foods and incorporate anti-inflammatory nutrients.
- Monitor & Retest: Conduct follow-up lab testing to assess progress and make necessary adjustments